Primary Open Angle Glaucoma: The Pathophysiolgy, Mechanisms, Future Diagnostic and Therapeutic Directions
نویسندگان
چکیده
منابع مشابه
Current primary open-angle glaucoma treatments and future directions
Primary open-angle glaucoma (POAG) is a leading cause of blindness with no known cure. Management of the disease focuses on lowering intraocular pressure (IOP) with current classes of drugs like prostaglandin analogs, beta-blockers, alpha-agonists, and carbonic anhydrase inhibitors. These treatments have not helped all patients. Some patients continue to experience deterioration in the optic ne...
متن کاملMECHANISMS OF DISEASE Primary Open-Angle Glaucoma
Copyright © 2009 Massachusetts Medical Society. Glaucoma is a chronic, degenerative optic neuropathy that can be distinguished from most other forms of acquired optic neuropathy by the characteristic appearance of the optic nerve. In glaucoma, the neuroretinal rim of the optic nerve becomes progressively thinner, thereby enlarging the optic-nerve cup. This phenomenon is referred to as optic-ner...
متن کاملPrimary open-angle glaucoma
Primary open-angle glaucoma (POAG) is an idiopathic disorder in which the resistance to outflow through the trabecular meshwork gradually increases and the intraocular pressure (IOP) rises, causing irreversible damage to the optic nerve POAG is the second most common cause of vision loss in the U.S. Usually asymptomatic until advanced visual field loss has occurred; less than 50% of those...
متن کاملprimary open-angle glaucoma risk factors
purpose: the objective of this study was to identify possible risk factors associated with primary open-angle glaucoma (poag). methods: a case-control study included patients seen at rasoul-akram hospital ophthalmology clinic. cases were consecutive patients with confirmed unilateral or bilateral poag presented during the study period. controls were a random sample of all other patients aged 30...
متن کاملThe genetics of primary open angle glaucoma.
The advent of the discipline of molecular genetics over the past decade has led to a dramatic growth in our understanding of the genetics of a myriad of diseases. Ophthalmology has benefited greatly from this new technology, with significant advances in our knowledge about conditions as varied as aniridia and retinitis pigmentosa. 2 Our understanding of the genetics of primary open angle glauco...
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ژورنال
عنوان ژورنال: Ophthalmology Research: An International Journal
سال: 2019
ISSN: 2321-7227
DOI: 10.9734/or/2019/v10i330106